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Octaarginine、R8、Arg8、(Arg)8
Name
Octaarginine、R8、Arg8、(Arg)8
Molecular structural formula
Purity
95%
CAS Number
148796-86-5
Formula
C48H98N32O9
MW
1267.5
Sequence
Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-OH
Sequence Shortening
rrrrrrrrr
InChIKey
IZYRKBFCCCZTDD-GZNSWUDSSA-N
References
[1]. Cellular uptake of arginine-rich peptides: roles for macropinocytosis and actin rearrangement. [2].The cell-penetrating peptide octa-arginine is a potent inhibitor of proteasome activities.
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Octaarginine R8's cell penetrating ability: Due to its positively charged nature, R8 octaarnine has strong cell penetration, able to penetrate the cell membrane and enter the cell's interior. This property makes it widely used in the study of drug delivery and gene delivery, which can combine with negatively charged drugs or nucleic acids (such as DNA, siRNA, etc.) to form complexes, and use its cell penetration to help these drugs or nucleic acids pass through the cell membrane and enter the cell to achieve the purpose of cell regulation.