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Synthesis of unnatural amino acids and other blocks

Val-Cit-PAB

Name
Val-Cit-PAB
Molecular structural formula
Purity
≥95%
CAS Number
159857-79-1
Formula
C45H64N12O9
MW
917.06
Target
ADC Linker
Sequence
Val-Cit-Pro-Ala-Bip-Orn-His-OH
Sequence Shortening
V-{Cit}-PA-{Bip-Orn}-H-OH
InChIKey
VEGGTWZUZGZKHY-GJZGRUSLSA-N
Solubility in DMSO
≥ 100 mg/mL
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Product details
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Val-Cit-PAB-OH is a peptide cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). The Val-Cit will specifically be cleaved by Cathepsin B.