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ACTH (4-10), human
Name
ACTH (4-10), human
Molecular structural formula
Purity
≥95%
CAS Number
4037-01-8
Formula
C44H59N13O10S
MW
962.1
Target
Melanocortin Receptor
Sequence
Met-Glu-His-Phe-Arg-Trp-Gly
Sequence Shortening
MEHFRWG
InChIKey
HAAUASBAIUJHAN-LXOXETEGSA-N
Solubility in DMSO
25mg/mL
Solubility in water
1mg/mL
References
[1]. Wellhöner P, et al. Intranasal application of the melanocortin 4 receptor agonist MSH/ACTH(4-10) in humans causes lipolysis in white adipose tissue. Int J Obes (Lond). 2012 May;36(5):703-8.
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Adrenocorticotropic Hormone (ACTH) (4-10), human (ACTH (4-10)) is the core sequence of all melanocortins and binds selectively to MC4-R. In humans, ACTH (4-10) enters the cerebral fluid compartment after intranasal application and leads to a decrease in total body fat after 6 weeks of continuous treatment.