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DOTA-NHS-ester
Name
DOTA-NHS-ester
Molecular structural formula
Purity
≥95%
CAS Number
1823122-52-6
Formula
C20H31N5O10.C2HF3O2.F6P.H
MW
761.48
Target
Biochemical Assay Reagents
Sequence
DOTA-NHS-ester
Sequence Shortening
DOTA-NHS-ester
InChIKey
XIICJKXKEDCZEE-UHFFFAOYSA-N
Solubility in DMSO
100 mg/mL
References
[1]. Wängler C, et, al. Improved syntheses and applicability of different DOTA building blocks for multiply derivatized scaffolds. Bioorg Med Chem. 2008 Mar 1; 16(5): 2606-16.
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DOTA-NHS-ester (hexafluorophosphate TFA)is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting. DOTA-NHS-ester (hexafluorophosphate TFA) can be used for conjugation of peptides and radionuclides.