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Deserelin
Name
Deserelin
Molecular structural formula
Purity
≥98%
CAS Number
57773-65-6
Formula
C64H83N17O12
MW
1282.48
Target
GnRH report
Sequence
Pyr-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-NHEt
Sequence Shortening
{Pyr}-HWSYWLRP-NHEt
InChIKey
GJKXGJCSJWBJEZ-XRSSZCMZSA-N
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Deslorelin acetate is an injectable gonadotropin releasing hormone super-agonist also known as an LHRH agonist. It stops the production of sex hormones.

Deslorelin is a synthetic nonapeptide analogue of the natural gonadotrophin releasing hormone (GnRH) with potential antineoplastic activity. Deslorelin binds to and activates pituitary gonadotropin releasing hormone (GnRH) receptors. Continuous, prolonged administration of goserelin in males results in pituitary GnRH receptor desensitization and inhibition of pituitary secretion of follicle stimulating hormone (FSH) and luteinizing hormone (LH), leading to a significant decline in testosterone production; in females, prolonged administration results in a decrease in estradiol production. (NCI04)