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Vapreotide
Name
Vapreotide
Molecular structural formula
Purity
≥98%
CAS Number
103222-11-3
Formula
C57H70N12O9S2
MW
1131.37
Target
Neurokinin Receptor
Sequence
{D-Phe}-Cys-Tyr-{D-Trp}-Lys-Val-Cys-Trp-NH2 (Disulfide bridge: Cys2-Cys7)
Sequence Shortening
{D-Phe}-CY-{D-Trp}-KVCW-NH2 (Disulfide bridge: Cys2-Cys7)
InChIKey
SWXOGPJRIDTIRL-UHFFFAOYSA-N
Solubility in water
100 mg/mL
References
[1]. Spitsin S et al. Analog of somatostatin vapreotide exhibits biological effects in vitro via interaction with neurokinin-1 receptor. Neuroimmunomodulation. 2013;20(5):247-55.
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Vapreotide is a neurokinin-1 (NK1) receptor antagonist, with an IC50 of 330 nM.