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Home / Peptide products / C (134 species) / CRF / Corticotropin Releasing Factor, bovine
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Corticotropin Releasing Factor, bovine
Name
Corticotropin Releasing Factor, bovine
Molecular structural formula
Purity
≥95%
CAS Number
92307-52-3
Formula
C206H340N60O63S
MW
4697.44
Target
CRFR
Sequence
Ser-Gln-Glu-Pro-Pro-Ile-Ser-Leu-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Met-Thr-Lys-Ala-Asp-Gln-Leu-Ala-Gln-Gln-Ala-His-Asn-Asn-Arg-Lys-Leu-Leu-Asp-Ile-Ala-NH2
Sequence Shortening
SQEPPISLDLTFHLLREVLEMTKADQLAQQAHNNRKLLDIA-NH2
InChIKey
BMUPKVLWWGQTIL-SFYWBPHXSA-N
References
[1]. Hogg JE, et al. The human neuroblastoma cell line, IMR-32, expresses functional corticotropin-releasing factor receptors. Eur J Pharmacol. 1996 Sep 26;312(2):257-61. [2]. Smart D, et al. Characterisation using microphysiometry of CRF receptor pharmacology. Eur J Pharmacol. 1999 Aug 27;379(2-3):229-35. [3]. Esposito P, et al. Corticotropin-releasing factor (CRF) can directly affect brain microvessel endothelial cells. Brain Res. 2003 Apr 11;968(2):192-8.
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Product details
Data download

CRF, bovine is a potent agonist of CRF receptor, and displaces [125I-Tyr]ovine CRF with a Ki of 3.52 nM.