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Home / Peptide products / G (123 species) / GIP / Gastric Inhibitory Peptide (GIP), human
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Gastric Inhibitory Peptide (GIP), human
Name
Gastric Inhibitory Peptide (GIP), human
Molecular structural formula
Purity
≥95%
CAS Number
100040-31-1
Formula
C226H338N60O66S
MW
4983.64
Target
Insulin Receptor
Sequence
Tyr-Ala-Glu-Gly-Thr-Phe-Ile-Ser-Asp-Tyr-Ser-Ile-Ala-Met-Asp-Lys-Ile-His-Gln-Gln-Asp-Phe-Val-Asn-Trp-Leu-Leu-Ala-Gln-Lys-Gly-Lys-Lys-Asn-Asp-Trp-Lys-His-Asn-Ile-Thr-Gln
Sequence Shortening
YAEGTFISDYSIAMDKIHQQDFVNWLLAQKGKKNDWKHNITQ
InChIKey
MGXWVYUBJRZYPE-UHFFFAOYSA-N
References
[1]. Meier JJ, et al. Gastric inhibitory polypeptide: the neglected incretin revisited. Regul Pept. 2002 Jul 15;107(1-3):1-13. [2]. Miyachi A, et al. Quantitative analytical method for determining the levels of gastric inhibitory polypeptides GIP1-42 and GIP3-42 in human plasma using LC-MS/MS/MS. J Proteome Res. 2013;12(6):2690-2699. [3]. Gabe MBN, et al. Molecular interactions of full-length and truncated GIP peptides with the GIP receptor - A comprehensive review. Peptides. 2020;125:170224.
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Product details
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GIP, human, a peptide hormone consisting of 42 amino acids, is a stimulator of glucose-dependent insulin secretion and a weak inhibitor of gastric acid secretion. GIP, human acts as an incretin hormone released from intestinal K cells in response to nutrient ingestion.