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Galanin, human
Name
Galanin, human
Molecular structural formula
Purity
≥95%
CAS Number
119418-04-1
Formula
C139H210N42O43
MW
3157.44
Target
Neuropeptide Y Receptor
Sequence
Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-His-Ala-Val-Gly-Asn-His-Arg-Ser-Phe-Ser-Asp-Lys-Asn-Gly-Leu-Thr-Ser
Sequence Shortening
GWTLNSAGYLLGPHAVGNHRSFSDKNGLTS
InChIKey
CBSXZYWGVAQSHI-RUKUCZSXSA-N
Solubility in water
1 mg/mL
References
[1]. Hua XY, et al. Galanin acts at GalR1 receptors in spinal antinociception: synergy with morphine and AP-5. J Pharmacol Exp Ther. 2004 Feb;308(2):574-82. [2]. Schmidt WE, et al. Isolation and primary structure of pituitary human galanin, a 30-residue nonamidated neuropeptide. Proc Natl Acad Sci U S A. 1991 Dec 15;88(24):11435-9.
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Galanin, a 29 or 30 (in human) amino acid neuropeptide, is found in the central and peripheral nervous systems and displays several important physiological activities. These actions are mediated through distinct G protein-coupled receptors.