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Galanin (2-11)
Name
Galanin (2-11)
Molecular structural formula
Purity
≥95%
CAS Number
367518-31-8
Formula
C54H81N13O14
MW
1136.33
Target
Neuropeptide Y Receptor
Sequence
Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-NH2
Sequence Shortening
WTLNSAGYLL-NH2
InChIKey
SUJPPMXJCZETOA-ZKEPBWIVSA-N
References
[1]. Liu HX, et al. Receptor subtype-specific pronociceptive and analgesic actions of galanin in the spinal cord: selective actions via GalR1 and GalR2 receptors. Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9960-4. [2]. Serebryakova L, et al. Galanin and its N-terminal fragments reduce acute myocardial infarction in rats. Peptides. 2019 Jan;111:127-131.
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Product details
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Galanin (2-11) is a GalR2 selective agonist with a binding IC50 of 1.76 nM for rat GalR2. AR-M1896 can be used for the research of acute myocardial infarction and neuropathic pain.