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Home / Peptide products / G (123 species) / Gp100 / G209-2M; gp100 (209-217)
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G209-2M; gp100 (209-217)
Name
G209-2M; gp100 (209-217)
Molecular structural formula
Purity
≥95%
CAS Number
181477-43-0
Formula
C47H74N10O14S
MW
1035.24
Target
others
Sequence
Ile-Met-Asp-Gln-Val-Pro-Phe-Ser-Val
Sequence Shortening
IMDQVPFSV
InChIKey
BDQMCYCLZBSYJZ-BBXCZNCNSA-N
References
[1]. Yang S, et al. Antimelanoma activity of CTL generated from peripheral blood mononuclear cells after stimulation with autologous dendritic cells pulsed with melanoma gp100 peptide G209-2M is correlated to TCR avidity. J Immunol. 2002 Jul 1;169(1):531-9. [2]. Ahmadzadeh M, et al. IL-2 and IL-15 each mediate de novo induction of FOXP3 expression in human tumor antigen-specific CD8 T cells. J Immunother. 2007 Apr;30(3):294-302.
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Disomotide (G209-2M) is a melanoma antigen that enhances the generation of cytotoxic T lymphocytes (CTL) recognizing native G209 as well as melanoma.