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Home / Peptide products / G (123 species) / Glucagon / Glucagon - Like Peptide 1 (7 - 37)
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Glucagon - Like Peptide 1 (7 - 37)
Name
Glucagon - Like Peptide 1 (7 - 37)
Molecular structural formula
Purity
≥95%
CAS Number
106612-94-6
Formula
C151H226N40O46
MW
3337.73
Target
GCCR
Sequence
His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly
Sequence Shortening
HAEGTFTSDVSSYLEGQAAKEFIAWLVKGRG
InChIKey
GCYXWQUSHADNBF-AAEALURTSA-N
Solubility in water
< 0.1 mg/mL
References
[1]. Sarrauste de Menthiere, C. et al. Structural requirements of the N-terminal region of GLP-1-[7-37]-NH2 for receptor interaction and cAMP production. European journal of medicinal chemistry 39, 473-480, doi:10.1016/j.ejmech.2004.02.002 (2004). [2]. Hargrove DM, et al. Glucose-dependent action of glucagon-like peptide-1 (7-37) in vivo during short- or long-term administration. Metabolism. 1995 Sep;44(9):1231-7.
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GLP-1(7-37) is an intestinal insulinotropic hormone that augments glucose induced insulin secretion.