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Fibrinogen-binding Peptide
Name
Fibrinogen-binding Peptide
Molecular structural formula
Purity
≥95%
CAS Number
137235-80-4
Formula
C25H39N7O8
MW
565.63
Target
others
Sequence
Glu-His-Ile-Pro-Ala
Sequence Shortening
EHIPA
InChIKey
VWJLJHZPMZGDDV-HOCDWTQPSA-N
Solubility in DMSO
83.33 mg/mL
References
[1]. Gartner TK, et al. The peptide Glu-His-Ile-Pro-Ala binds fibrinogen and inhibits platelet aggregation and adhesion to fibrinogen and vitronectin. Proc Soc Exp Biol Med. 1991 Oct;198(1):649-55.
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Fibrinogen-Binding Peptide (designed by anticomplementarity hypothesis) is a presumptive peptide mimic of the vitronectin binding site on the fibrinogen receptor. Fibrinogen-Binding Peptide binds fibrinogen and inhibits both the adhesion of platelets to fibrinogen and platelet aggregation, and also inhibits the adhesion of platelets to vitronectin.