α-Helical CRF (9-41) CAS:90880-23-2 Sequence:DLTFHLLREMLEMAKAEQEAEQAALNRLLLEEA-NH2 Motifbiotech

CRO

CDMO

CMO

Testing services

Scientific Customized Peptides

General linear peptide synthesis

Long peptide synthesis

Cyclic peptide synthesis (staple peptide)

Cyclic peptide synthesis (disulfide ring formation)

Stable isotope labeling peptide synthesis

Glycopeptides

Polypeptide modification

Peptide library synthesis

Linker Synthesis Service

ADC Linker Synthesis Service

PDC Drug Synthesis Services

FTE Services

PEPTIDE FTE

Popular peptides

Beauty peptides

Drug peptide intermediates and impurities

Cancer antigenic peptide

Catalog peptides

Linker

Synthesis of unnatural amino acids and other blocks

Human body system

HA 12CA5 Epitope

Cys-Angiopep-2

[Ala9]Autocamtide2

(Val²)-Amyloid β-Protein (1-42)

N-Acetyl lysyltyrosylcysteine amide

Acetyl-(D-Arg10,Cys11,D-Phe14,Cys17)-β-MSH (10-17) amide

MPG

Ganirelix

Bioanalytical drug development

Ac-RADARADARADARADAYKKIIKKLRGDSP-NH2

Boc-VLGR-pNA

DADE-S(OGlcNAc)-L

c(His-Phe)

Suc-GP-AMC

Cell Adhesive Peptide [RGDC]

HSV-1-amide UL 26 Open Reading Frame (242-255)

RRAAEELDSRAG-S(OGlcNAc)-PQL

Nano Peptide

DArg9

RADA16

Hel 13-5

LIVAGD

Cadherin Peptide , avian

LF-NH2

FITC-LC-TAT (47-57)

LF

Home / Peptide products / C (134 species) / CRF / α-Helical CRF (9-41)

Filters

Popular peptides

Human body system

Tripeptide Peptide Tag Domain Antagonist peptides Blocker Peptides Antimicrobial peptides Amyloid peptides Inhibitor peptides Targeted Peptide Agonist Peptide

Bioanalytical drug development

RGD Peptides Glycopeptides Dipeptide Cyclodipeptide Substrate Peptide

Nano Peptide

Self-assembling peptides Cell-penetrating Peptides

Beauty peptides

Anti-aging

Anti-inflammatory

Repair

Moisturizing

Whitening

Body care

Drug peptide intermediates and impurities

Neoplasm

Diabetes mellitus

Cardiovascular

Reproductive

Anti-infection

Osteoporosis

Other

Cancer antigenic peptide

Mutation

Differentiation

Overexpressed

Tumor-specific

Catalog peptides

Linker

ADC Linker

Peptide Linker

PDC Linker

RDC linker

PROTAC linker

Reactive Linker

Alkyne Reactive Linker Amine Reactive Linker Azide Reactive Linker Click Reactive Linker Thiol Reactive Linker

Linker Intermediate

Advanced Linker Intermediate

Synthesis of unnatural amino acids and other blocks

Fmoc protects unnatural amino acids

α-Helical CRF (9-41)

Support

Name α-Helical CRF (9-41)	Molecular structural formula
Purity ≥95%
CAS Number 90880-23-2
Formula C166H274N46O53S2
MW 3826.44
Target CRFR
Sequence Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Glu-Met-Leu-Glu-Met-Ala-Lys-Ala-Glu-Gln-Glu-Ala-Glu-Gln-Ala-Ala-Leu-Asn-Arg-Leu-Leu-Leu-Glu-Glu-Ala-NH2
Sequence Shortening DLTFHLLREMLEMAKAEQEAEQAALNRLLLEEA-NH2
InChIKey PNGVJHODDQMQKT-GVKLFNHCSA-N
Solubility in water 50 mg/mL
References [1]. Sonia Tucci, et al. Corticotropin releasing factor antagonist, alpha-helical CRF(9-41), reverses nicotine-induced conditioned, but not unconditioned, anxiety. Psychopharmacology (Berl). 2003 May;167(3):251-6. [2]. Smart D, et al. Characterisation using microphysiometry of CRF receptor pharmacology. Eur J Pharmacol. 1999 Aug 27;379(2-3):229-35.

* All products on our website are for scientific research and cannot be used in human body

Product details

Data download

α-Helical CRF(9-41) is a competitive CRF2 receptor antagonist with KB of ~100 nM. α-Helical CRF(9-41) is also a partial agonist of CRF1 receptor with an EC50 of 140 nM.