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Home / Peptide products / A (265 species) / Amyloid / β- Amyloid (1-40)
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β- Amyloid (1-40)
Name
β- Amyloid (1-40)
Molecular structural formula
Purity
≥95%
CAS Number
131438-79-4
Formula
C194H295N53O58S
MW
4329.82
Target
Amyloid-β
Sequence
Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val
Sequence Shortening
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV
InChIKey
FEWOUVRMGWFWIH-UHFFFAOYSA-N
Solubility in DMSO
50mg/mL
Solubility in water
50mg/mL
References
[1]. Shoji M, et al. Cerebrospinal fluid Abeta40 and Abeta42: natural course and clinical usefulness. Front Biosci. 2002 Apr 1;7:d997-1006. [2]. Cleary J, et al. Beta-amyloid(1-40) effects on behavior and memory. Brain Res. 1995 Jun 5;682(1-2):69-74. [3]. Olariu A, et al. Memory impairment induced by chronic intracerebroventricular infusion of beta-amyloid (1-40) involves downregulation of protein kinase C. Brain Res. 2002 Dec 13;957(2):278-86.
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β-Amyloid (1-40) is a primary protein in plaques found in the brains of patients with Alzheimer's disease.