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Synthesis of unnatural amino acids and other blocks
ANP (1-30), frog
Name
ANP (1-30), frog
Molecular structural formula
Purity
≥95%
CAS Number
309245-16-7
Formula
C131H215N49O41S4
MW
3260.73
Target
Endothelin Receptor
Sequence
Ala-Pro-Arg-Ser-Met-Arg-Arg-Ser-Ser-Asp-Cys-Phe-Gly-Ser-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Met-Gly-Cys-Gly-Arg-Phe(Disulfide bridge:Cys11-Cys27)
Sequence Shortening
APRSMRRSSDCFGSRIDRIGAQSGMGCGRF(Disulfide bridge:Cys11-Cys27)
References
[1]. Cannone V, et al. Atrial Natriuretic Peptide: A Molecular Target of Novel Therapeutic Approaches to Cardio-Metabolic Disease. Int J Mol Sci. 2019 Jul 2;20(13):3265.
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ANP (1-30), frog is a peptide fragment of atrial natriuretic peptide derived from frog. ANP (1-30), frog has natriuretic, diuretic, and vasorelaxant effects.