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Amyloid β-Protein (5-42)
Name
Amyloid β-Protein (5-42)
Molecular structural formula
Purity
95%
CAS Number
1678415-97-8
Formula
C182H285N51O52S1
MW
4051.59
Target
Amyloid-β
Sequence
Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala
Sequence Shortening
RHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
References
[1].Amino-truncated amyloid beta-peptide (Abeta5-40/42) produced from caspase-cleaved amyloid precursor protein is deposited in Alzheimer's disease brain.
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Abeta 5-42 is produced from amyloid precursor protein by action of caspases. It is deposited in Alzheimer's disease brain as well, but less prone to aggregation.