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Synthesis of unnatural amino acids and other blocks
[Nle11] Substance P
Name
[Nle11] Substance P
Molecular structural formula
Purity
≥95%
CAS Number
57462-42-7
Formula
C64H100N18O13
MW
1329.62
Target
Neurokinin Receptor
Sequence
Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Nle-NH2
Sequence Shortening
RPKPQQFFGL-{NLE}-NH2
InChIKey
ZEPTUBCWHRSMIP-UHFFFAOYSA-N
References
[1]. Chipkin RE, et al. In vitro activities of some synthetic substance P analogs. Arch Int Pharmacodyn Ther. 1979 Aug;240(2):193-202.
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[Nle11]-Substance P is a substance P analog that avoids methionine oxidation problems.