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Home / Peptide products / P (129 species) / PACAP / PACAP-38 (16-38) (human, chicken, mouse, ovine, porcine, rat)
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PACAP-38 (16-38) (human, chicken, mouse, ovine, porcine, rat)
Name
PACAP-38 (16-38) (human, chicken, mouse, ovine, porcine, rat)
Molecular structural formula
Purity
≥95%
CAS Number
144025-82-1
Formula
C123H215N39O28S
MW
2720.37
Target
PACAP Receptor
Sequence
Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-Gly-Lys-Arg-Tyr-Lys-Gln-Arg-Val-Lys-Asn-Lys-NH2
Sequence Shortening
QMAVKKYLAAVLGKRYKQRVKNK-NH2
References
[1]. Braas KM, et al. Pituitary adenylate cyclase-activating polypeptides, PACAP-38 and PACAP-27, regulation of sympathetic neuron catecholamine, and neuropeptide Y expression through activation of type I PACAP/VIP receptor isoforms. Ann N Y Acad Sci. 1996 Dec 26;805:204-16. [2]. Lania A, et al. Mechanism of action of pituitary adenylate cyclase-activating polypeptide (PACAP) in human nonfunctioning pituitary tumors. J Neuroendocrinol. 1995 Sep;7(9):695-702.
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Product details
Data download

PACAP-38 (16-38), human, mouse, rat demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY and catecholamine production. PACAP is a potent activator of cAMP formation.