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Home / Peptide products / Human body system / Domain / [Lys1015, 1024]-Thrombospondin-1(1015-1024), human
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[Lys1015, 1024]-Thrombospondin-1(1015-1024), human
Name
[Lys1015, 1024]-Thrombospondin-1(1015-1024), human
Molecular structural formula
Purity
95%
CAS Number
178921-95-4
Formula
C68H105N17O12S1
MW
1384.73
Target
Others
Sequence
Lys-Arg-Phe-Tyr-Val-Val-Met-Trp-Lys-Lys
Sequence Shortening
KRFYVVMWKK
InChIKey
XEMLJJZYMPZGBS-ITJFCMOYSA-N
Solubility in DMSO
100 mg/mL
References
[1]. Involvement of a CD47-dependent pathway in platelet adhesion on inflamed vascular endothelium under flow. [2].Thrombospondin-bound integrin-associated protein (CD47) physically and functionally modifies integrin alphaIIbbeta3 by its extracellular domain. [3]. Thrombospondin modulates alpha v beta 3 function through integrin-associated protein. [4].The thrombospondin receptor CD47 (IAP) modulates and associates with alpha2 beta1 integrin in vascular smooth muscle cells.
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Product details
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Integrin-associated protein (IAP/CD47) agonist peptide, 4N1K (KRFYVVMWKK), derived from the cell binding domain of thrombospondin-1 (TS1). The peptide has been shown to stimulate integrin-dependent cell functions, including platelet aggregation.