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Fmoc-NH-PEG4-CH2CH2COOH
Name
Fmoc-NH-PEG4-CH2CH2COOH
Molecular structural formula
Purity
≥95%
CAS Number
557756-85-1
Formula
C26H33NO8
MW
487.54
Target
ADC Linker
InChIKey
NUHRPLKTAAVHCZ-UHFFFAOYSA-N
Solubility in DMSO
100 mg/mL
References
[1]. Cai P, et al. Synthesis of C3-Alkylated Indoles on DNA via Indolyl Alcohol Formation Followed by Metal-FreeTransfer Hydrogenation. Org Lett. 2019 Aug 14.
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Fmoc-NH-PEG4-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG4-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.