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Synthesis of unnatural amino acids and other blocks
Mc-Val-Cit-PABOH
Name
Mc-Val-Cit-PABOH
Molecular structural formula
Purity
≥95%
CAS Number
159857-80-4
Formula
C28H40N6O7
MW
572.65
Target
ADC Linker
InChIKey
AMKBTTRWLGVRER-OFVILXPXSA-N
Solubility in DMSO
100 mg/mL
References
[1]. Anti-cd70 antibody-drug conjugates and their use for the treatment of cancer and immune disorders
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MC-Val-Cit-PAB is an intermediate in the synthesis of VcMMAE , which is a Drug-Linker Conjugates for ADC. Monomethyl auristatin E can be used to inhibit Microtubule/Tubulin as ADC Cytotoxin.