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Home / Peptide products / I (62 species) / IGF / rec IGF-II (1-67) (human)
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rec IGF-II (1-67) (human)
Name
rec IGF-II (1-67) (human)
Molecular structural formula
Purity
≥95%
CAS Number
96081-16-2
Formula
C24H36N4O9
MW
524.564
Target
others
Sequence
Ala-Tyr-Arg-Pro-Ser-Glu-Thr-Leu-Cys-Gly-Gly-Glu-Leu-Val-Asp-Thr-Leu-Gln-Phe-Val-Cys-Gly-Asp-Arg-Gly-Phe-Tyr-Phe-Ser-Arg-Pro-Ala-Ser-Arg-Val-Ser-Arg-Arg-Ser-Arg-Gly-Ile-Val-Glu-Glu-Cys-Cys-Phe-Arg-Ser-Cys-Asp-Leu-Ala-Leu-Leu-Glu-Thr-Tyr-Cys-Ala-Thr-Pro
Sequence Shortening
AYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSRGIVEECCFRSCDLALLETYCAT
InChIKey
CPOKMHRJZDYBFO-UHFFFAOYSA-N
References
[1].Inhibition of proliferation in human MNNG/HOS osteosarcoma and SK-ES-1 Ewing sarcoma cell lines in vitro and in vivo by antagonists of growth hormone-releasing hormone: effects on insulin-like growth factor II. [2].Effect of mild hypoinsulinemia on renal hypertrophy: growth hormone/insulin-like growth factor I system in mild streptozotocin diabetes. [3].Zinc alters the kinetics of IGF-II binding to cell surface receptors and binding proteins.
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Product details
Data download

approx. ED₅₀ = 0.1 ng/mL IGF-II seems to be specifically involved in fetal growth, but otherwise shows similar biological activities to IGF-I.