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Home / Peptide products / M (76 species) / MCH / Melanin Concentrating Hormone, salmon MCH, salmon
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Melanin Concentrating Hormone, salmon MCH, salmon
Name
Melanin Concentrating Hormone, salmon MCH, salmon
Molecular structural formula
Purity
≥95%
CAS Number
87218-84-6
Formula
C89H137N27O24S4
MW
2097.9
Target
MCHR1 (GPR24)
Sequence
Asp-Thr-Met-Arg-Cys-Met-Val-Gly-Arg-Val-Tyr-Arg-Pro-Cys-Trp-Glu-Val(Disulfide bridge:Cys5-Cys14)
Sequence Shortening
DTMRCMVGRVYRPCWEV (Disulfide bridge: Cys5-Cys14)
InChIKey
ORRDHOMWDPJSNL-KHBOZDSRSA-N
References
[1]. An S, et al. Identification and characterization of a melanin-concentrating hormone receptor. Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7576-81. [2]. Della-Zuana O, et al. Acute and chronic administration of melanin-concentrating hormone enhances food intake and body weight in Wistar and Sprague-Dawley rats. Int J Obes Relat Metab Disord. 2002 Oct;26(10):1289-95. [3]. Gomori A, et al. Chronic intracerebroventricular infusion of MCH causes obesity in mice. Melanin-concentrating hormone. Am J Physiol Endocrinol Metab. 2003 Mar;284(3):E583-8. Epub 2002 Nov 26.
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Melanin Concentrating Hormone, salmon is a 19-amino-acid neuropeptide initially identified in the pituitary gland of teleost fish, which regulates food intake, energy balance, sleep state, and the cardiovascular system. Melanin-concentrating hormone is a ligand for an orphan G protein-coupled receptor (SLC-1/GPR24) and MCHR2.