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Synthesis of unnatural amino acids and other blocks
Mastoparan 7
Name
Mastoparan 7
Molecular structural formula
Purity
≥95%
CAS Number
145854-59-7
Formula
C67H124N18O15
MW
1421.85
Target
others
Sequence
Ile-Asn-Leu-Lys-Ala-Leu-Ala-Ala-Leu-Ala-Lys-Ala-Leu-Leu-NH2
Sequence Shortening
INLKALAALAKALL-NH2
InChIKey
HOLQXBRPSSZJMZ-FGRXCANLSA-N
References
[1]. Bavec A, et al. Novel features of amphiphilic peptide Mas7 in signalling via heterotrimeric G-proteins. J Pept Sci. 2004 Nov;10(11):691-9. [2]. Grześk G, et al. Direct regulation of vascular smooth muscle contraction by mastoparan-7. Biomed Rep. 2014 Jan;2(1):34-38. [3]. Ramírez VT, et al. The Gαo Activator Mastoparan-7 Promotes Dendritic Spine Formation in Hippocampal Neurons. Neural Plast. 2016;2016:4258171.
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Mas7 (Mastoparan 7), a structural analogue of mastoparan, is an activator of heterotrimeric Gi proteins and its downstream effectors.