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Mastoparan X
Name
Mastoparan X
Molecular structural formula
Purity
≥95%
CAS Number
72093-22-2
Formula
C73H126N20O15S
MW
1556.01
Target
Endogenous Metabolite
Sequence
Ile-Asn-Trp-Lys-Gly-Ile-Ala-Ala-Met-Ala-Lys-Lys-Leu-Leu-NH2
Sequence Shortening
INWKGIAAMAKKLL-NH2
InChIKey
FYJKBFOGJAVCAL-MRBAVNCWSA-N
Solubility in DMSO
≥ 100 mg/mL
References
[1]. Wakamatsu K, et al. Membrane-bound conformation of mastoparan-X, a G-protein-activating peptide. Biochemistry. 1992 Jun 23;31(24):5654-60. [2]. Whiles JA, et al. Orientation and effects of mastoparan X on phospholipid bicelles. Biophys J. 2001 Jan;80(1):280-93.
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Mastoparan X is a GTP-binding regulatory protein (G protein)-activating peptide, and a tetradecapeptide from wasp venom. Mastoparan X acts function by the direct activation of G protein that couple to phospholipase C to cause secretion from various kinds of cells.