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Home / Peptide products / E (116 species) / Endothelin / Endothelin-1, human
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Endothelin-1, human
Name
Endothelin-1, human
Molecular structural formula
Purity
≥95%
CAS Number
117399-94-7
Formula
C109H159N25O32S5
MW
2491.95
Target
Endothelin Receptor
Sequence
Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr- Phe-Cys-His-Leu-Asp-Ile-Ile-Trp(Disulfide bridge:Cys1-Cys15, Cys3-Cys11)
Sequence Shortening
CSCSSLMDKECVYFCHLDIIW (Disulfide bridge: Cys1-Cys15, Cys3-Cys11)
InChIKey
ZUBDGKVDJUIMQQ-UHFFFAOYSA-N
Solubility in water
0.99mg/mL
References
[1]. Kowalczyk A, et al. The role of endothelin-1 and endothelin receptor antagonists in inflammatory response andsepsis. Arch Immunol Ther Exp (Warsz). 2015 Feb;63(1):41-52.
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Product details
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Endothelin 1 (swine, human) is a synthetic peptide with the sequence of human and swine Endothelin 1, which is a potent endogenous vasoconstrictor. Endothelin 1 acts through two types of receptors ETA and ETB.