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Sinapultide
Name
Sinapultide
Molecular structural formula
Purity
≥98%
CAS Number
138531-07-4
Formula
C126H238N26O22
MW
2469.4
Target
Biochemical Assay Reagents
Sequence
Lys-Leu-Leu-Leu-Leu-Lys-Leu-Leu-Leu-Leu-Lys-Leu-Leu-Leu-Leu-Lys-Leu-Leu-Leu-Leu
Sequence Shortening
KLLLLKLLLLKLLLLKLLLL
InChIKey
QSIRXSYRKZHJHX-TWXHAJHVSA-N
References
[1]. Braide-Moncoeur O, et al. Peptide-based synthetic pulmonary surfactant for the treatment of respiratory distress disorders. Curr Opin Chem Biol. 2016 Jun;32:22-8. [2]. Liu D, et al. Sinapultide-Loaded Microbubbles Combined with Ultrasound to Attenuate Lipopolysaccharide-Induced Acute Lung Injury in Mice. Drug Des Devel Ther. 2020 Dec 22;14:5611-5622.
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Sinapultide is a 21-amino-acid peptide that mimics the action of human surfactant protein-B (SP-B). Sinapultide can be used for synthetic phospholipids surfactants improvement.