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Home / Peptide products / A (265 species) / Atriopeptin / Atriopeptin III (rat)
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Atriopeptin III (rat)
Name
Atriopeptin III (rat)
Molecular structural formula
Purity
≥95%
CAS Number
90817-13-3
Formula
C107H165N35O34S2
MW
2549.85
Target
others
Sequence
Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr(Disulfide bridge:Cys3-Cys19)
Sequence Shortening
SSCFGGRIDRIGAQSGLGCNSFRY(Disulfide bridge:Cys3-Cys19)
InChIKey
AYCBRUDZNRVKGK-GWLSAQFNSA-N
References
[1]. Olsen UB, et al. Atriopeptin III improves renal functions in a ureter-obstructed rat kidney model. Eur J Pharmacol. 1986 Mar 18;122(2):191-6. [2]. Cole BR, et al. Atriopeptin III. A potent natriuretic, diuretic, and hypotensive agent in rats with chronic renal failure. J Clin Invest. 1985 Dec;76(6):2413-5.
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Atriopeptin III  (rat), a 24-amino acid atrial peptide, is a potent vasodilator and natriuretic/diuretic agent. Atriopeptin III (rat) improves renal functions and decreases blood pressure in a ureter-obstructed rat kidney model. Atriopeptin III (rat) can be used for research of chronic renal failure.