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γ-Neuropeptide, rabbit

Name
γ-Neuropeptide, rabbit
Molecular structural formula
Purity
≥95%
CAS Number
114882-65-4
Formula
C99H158N34O29S
MW
2320.64
Target
Neurokinin Receptor
Sequence
Asp-Ala-Gly-His-Gly-Gln-Ile-Ser-His-Lys-Arg-His-Lys-Thr-Asp-Ser-Phe-Val-Gly-Leu-Met-NH2
Sequence Shortening
DAGHGQISHKRHKTDSFVGLM-NH2
InChIKey
NISSWFHUIGHJLY-DKRDOARVSA-N
References
[1]. Kage R, et al. Neuropeptide-gamma: a peptide isolated from rabbit intestine that is derived from gamma-preprotachykinin. J Neurochem. 1988 May;50(5):1412-7. [2]. Yuan L, et al. Characterization of tachykinin receptors mediating bronchomotor and vasodepressor responses to neuropeptide gamma and substance P in the anaesthetized rabbit. Pulm Pharmacol Ther. 1998 Feb;11(1):31-9. [3]. Debeljuk L, et al. Modulation of the hypothalamo-pituitary-gonadal axis and the pineal gland by neurokinin A, neuropeptide K and neuropeptide gamma. Peptides. 1999;20(2):285-99. [4]. Kalra PS, et al. Diverse effects of tachykinins on luteinizing hormone release in male rats: mechanism of action. Endocrinology. 1992 Sep;131(3):1195-201. [5]. Debeljuk L, et al. In vivo and in vitro effects of neuropeptide K and neuropeptide gamma on the release of growth hormone. Neuroreport. 1995 Dec 15;6(18):2457-60.
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Product details
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γ-Neuropeptide (rabbit) can be isolated from rabbit intestine. γ-Neuropeptide is an endogenous neurokinin peptide that acts as a neurokinin 2 (NK2) receptor agonist. γ-Neuropeptide mediates hypothalamic-pituitary-adrenal (HPA) axis, as well as reproductive hormone release.