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β-Endorphin (6-31), human

Name
β-Endorphin (6-31), human
Molecular structural formula
Purity
≥95%
CAS Number
77761-27-4
Formula
C131H218N34O40
MW
2909.4
Target
Opioid Receptor
Sequence
Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Ala-Tyr-Lys-Lys-Gly-Glu
Sequence Shortening
TSEKSQTPLVTLFKNAIIKNAYKKGE
InChIKey
WCOFQMXJGOCODK-JXBHHXAKSA-N
References
[1]. Introini IB, et al. The impairment of retention induced by beta-endorphin in mice may be mediated by a reduction of central cholinergic activity. Behav Neural Biol. 1984 Jul;41(2):152-63.
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β-Endorphin, an endogenous opioid neuropeptide, is an opioid receptor agonist. β-Endorphin binds preferentially to μ-opioid receptors and is produced in certain neurons of the central and peripheral nervous system and is one of three endorphins produced in humans. β-Endorphin can be used to reduce stress and maintain homeostasis in the body and is involved in neurological pain perception regulation.