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α-helical CRF 9-41 acetate

Name
α-helical CRF 9-41 acetate
Molecular structural formula
Purity
95%
CAS Number
99658-03-4
Formula
C166H274N46O53S2
MW
3826.36
Target
CRFR
Sequence
Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Glu-Met-Leu-Glu-Met-Ala-Lys-Ala-Glu-Gln-Glu-Ala-Glu-Gln-Ala-Ala-Leu-Asn-Arg-Leu-Leu-Leu-Glu-Glu-Ala-NH2
Sequence Shortening
DLTFHLLREMLEMAKAEQEAEQAALNRLLLEEA-NH2
InChIKey
QDUCLNZKQMUVKX-MJGOQNOKSA-N
References
[1]. Rivier C, Vale W. Involvement of corticotropin-releasing factor and somatostatin in stress-induced inhibition of growth hormone secretion in the rat. Endocrinology. 1985 Dec;117(6):2478-82. [2]. Takakazu Oka, et al. Intracerebroventricular injection of interleukin-1/β induces hyperalgesia in rats. Brain Research, 624 (1993) 61-68.
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Product details
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α-helical CRF 9-41 acetate, a salt of α-helical CRF 9-41 that is a competitive CRF2 receptor antagonist and a partial agonist of CRF1 receptor.