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Home / Peptide products / Catalog peptides / M (76 species) / Melanocyte Protein /
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α-MSH

Name
α-MSH
Molecular structural formula
Purity
≥95%
CAS Number
581-05-5
Formula
C77H109N21O19S
MW
1664.9
Target
Melanocortin Receptor
Sequence
Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2
Sequence Shortening
Ac-SYSMEHFRWGKPV-NH2
InChIKey
WHNFPRLDDSXQCL-UAZQEYIDSA-N
Solubility in DMSO
100 mg/mL
Solubility in water
25 mg/mL
References
[1]. Madhuri Singh, et al. C-terminal amino acids of alpha-melanocyte-stimulating hormone are requisite for its antibacterial activity against Staphylococcus aureus. Antimicrob Agents Chemother. 2011 May;55(5):1920-9. [2]. M S Kim, et al. Hypothalamic localization of the feeding effect of agouti-related peptide and alpha-melanocyte-stimulating hormone. Diabetes. 2000 Feb;49(2):177-82. [3]. Lipton JM, et al. Mechanisms of antiinflammatory action of alpha-MSH peptides. In vivo and in vitro evidence. Ann N Y Acad Sci. 1999;885:173-182.
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Product details
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α-MSH (α-Melanocyte-Stimulating Hormone), an endogenous neuropeptide, is an endogenous melanocortin receptor 4 (MC4R) agonist with anti-inflammatory and antipyretic activities. α-MSH is a post-translational derivative of pro-opiomelanocortin (POMC).