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Synthesis of unnatural amino acids and other blocks

Thymalfasin

Name
Thymalfasin
Molecular structural formula
Purity
≥98%
CAS Number
62304-98-7
Formula
C129H215N33O55
MW
3108.28
Target
Influenza Virus
Sequence
Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn
Sequence Shortening
Ac-SDAAVDTSSEITTKDLKEKKEVVEEAEN
InChIKey
NZVYCXVTEHPMHE-ZSUJOUNUSA-N
Solubility in water
0.3 mg/mL
References
[1]. Lao X et al. A modified thymosin alpha 1 inhibits the growth of breast cancer both in vitro and in vivo: suppressment of cell proliferation, inducible cell apoptosis and enhancement of targeted anticancer effects. Apoptosis. 2015 Oct;20(10):1307-20. [2]. Sjogren MH et al. Thymalfasin: an immune system enhancer for the treatment of liver disease. J Gastroenterol Hepatol. 2004 Dec;19(12):S69-72.
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Thymosin is a polypeptide immunomodulator composed of 28 amino acids. Its main function is to enhance the Th1 immune response, improve the function and maturity of T cells, and increase the level of lymphokines, thereby enhancing the body's immune defense capabilities.