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Synthesis of unnatural amino acids and other blocks

Tetracosactide Tetracosactrin

Name
Tetracosactide Tetracosactrin
Molecular structural formula
Purity
≥98%
CAS Number
16960-16-0
Formula
C136H210N40O31S
MW
2933.44
Target
others
Sequence
Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys -Val-Tyr-Pro
Sequence Shortening
SYSMEHFRWGKPVGKKRRPVKVYP
InChIKey
ZOEFCCMDUURGSE-SQKVDDBVSA-N
Solubility in water
100 mg/mL
References
[1]. Francesco Iuliano, et al. Adding Slow Release Tetracosactide Acetate to Eltrombopag Improves Haematological Response in ITP Patients with Platelet-Count Fluctuation. 2018 Nov 29;132(1).
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Tetracosactide, also known as tetracoseptide corticotropin or synthetic corticotropin, is a synthetic polypeptide composed of 24 amino acids. Its biological activity is very similar to adrenocorticotropic hormone (ACTH), and it can effectively promote the adrenal gland to secrete steroid hormones such as cortisol.