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Synthesis of unnatural amino acids and other blocks

Tetracosactide Acetate

Name
Tetracosactide Acetate
Molecular structural formula
Purity
≥98%
CAS Number
16960-16-0
Formula
C136H210N40O31S
MW
2933.4
Target
others
Sequence
Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro
Sequence Shortening
SYSMEHFRWGKPVGKKRRPVKVYP
InChIKey
ZOEFCCMDUURGSE-SQKVDDBVSA-N
Solubility in water
100mg/mL
References
[1]. Francesco Iuliano, et al. Adding Slow Release Tetracosactide Acetate to Eltrombopag Improves Haematological Response in ITP Patients with Platelet-Count Fluctuation. 2018 Nov 29;132(1).
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Tetracosactide Acetate (Tetracosactrin) is an analogue of adrenocorticotrophic hormone (ACTH), Tetracosactide Acetate can stimulate the release of corticosteroids such as cortisol from the adrenal gland. Tetracosactide is currently used for the research of ulcerative colitis and Crohn's disease, juvenile/adult rheumatoid arthritis and osteoarthrosis