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Synthesis of unnatural amino acids and other blocks

Teriparatide

Name
Teriparatide
Molecular structural formula
Purity
≥98%
CAS Number
52232-67-4
Formula
C181H291N55O51S2
MW
4117.72
Target
others
Sequence
Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe
Sequence Shortening
SVSEIQLMHNLGKHLNSMERVEWLRKKLQDVHNF
InChIKey
OGBMKVWORPGQRR-UMXFMPSGSA-N
Solubility in water
100 mg/mL
References
[1]. Iwamoto J, et, al. Influence of Teriparatide and Ibandronate on Cortical Bone in New Zealand White Rabbits: A HR-QCT Study. Calcif Tissue Int. 2016
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Teriparatide is a synthetic 34-mer peptide with a structure similar to parathyroid hormone that promotes bone formation and bone resorption. It accelerates bone growth by enhancing the activity and number of osteoblasts and acts directly on the body's bone cells.