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Teduglutide

Name
Teduglutide
Molecular structural formula
Purity
≥98%
CAS Number
197922-42-2
Formula
C164H252N44O55S
MW
3752.08
Target
others
Sequence
His-Gly-Asp-Gly-Ser-Phe-Ser-Asp-Glu-Met-Asn-Thr-Ile-Leu-Asp-Asn-Leu-Ala-Ala-Arg-Asp-Phe-Ile-Asn-Trp-Leu-Ile-Gln-Thr-Lys-Ile-Thr-Asp
Sequence Shortening
HGDGSFSDEMNTILDNLAARDFINWLIQTKITD
InChIKey
CILIXQOJUNDIDU-ASQIGDHWSA-N
Solubility in DMSO
22.22 mg/mL
Solubility in water
50 mg/mL
References
[1]. Jeppesen PB, et al. Teduglutide (ALX-0600), a dipeptidyl peptidase IV resistant glucagon-like peptide 2 analogue, improves intestinal function in short bowel syndrome patients. Gut. 2005 Sep;54(9):1224-31. [2]. Buchman AL, et al; Teduglutide Study Group. Teduglutide, a novel mucosally active analog of glucagon-like peptide-2 (GLP-2) for the treatment of moderate to severe Crohn's disease. Inflamm Bowel Dis. 2010 Jun;16(6):962-73.
* All products on our website are for scientific research and cannot be used in human body
Product details
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Teduglutide is a dipeptidyl peptidase IV resistant glucagon-like peptide 2 (GLP-2) analogue. Teduglutide is associated with trophic effects on gut mucosa. Teduglutide can be used for the research of short bowel syndrome (SBS) and Crohn's disease (CD).