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Home / Peptide products / Catalog peptides / E (116 species) / Endothelin /
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Succinyl-(Glu9,Ala11,15)-Endothelin-1 (8-21)

Name
Succinyl-(Glu9,Ala11,15)-Endothelin-1 (8-21)
Molecular structural formula
Purity
≥95%
CAS Number
142569-99-1
Formula
C86H118N17O27
MW
1821
Target
Endothelin Receptor
Sequence
Suc-Asp-Glu-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp
Sequence Shortening
{Suc}-DEEAVYFAHLDIIW
InChIKey
DXPHNGAMYPPTBJ-TZMIJSMNSA-N
References
[1]. Takai M, et al. A potent and specific agonist, Suc-[Glu9,Ala11,15]-endothelin-1(8-21), IRL 1620, for the ETB receptor. Biochem Biophys Res Commun. 1992 Apr 30;184(2):953-9. [Content Brief] [2]. Briyal S, et al. Stimulation of endothelin B receptors by IRL-1620 decreases the progression of Alzheimer's disease. Neuroscience. 2015 Aug 20;301:1-11.
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Product details
Data download

Succinyl-(Glu9,Ala11,15)-Endothelin-1 (8-21) is a potent and selective endothelin receptor type B (ETB) agonist with a Ki of 16 pM.