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Substance P (1-7)

Name
Substance P (1-7)
Molecular structural formula
Purity
≥95%
CAS Number
68060-49-1
Formula
C41H65N13O10
MW
900.06
Target
Neurokinin Receptor
Sequence
Arg-Pro-Lys-Pro-Gln-Gln-Phe
Sequence Shortening
RPKPQQF
InChIKey
KPHDBQWTCKBKIL-UHFFFAOYSA-N
References
[1]. Herrera-Marschitz M, et al. The substance P(1-7) fragment is a potent modulator of substance P actions in the brain. Brain Res. 1990 Jun 25;521(1-2):316-20. [2]. Sakurada T, et al. Substance P(1-7) antagonizes substance P-induced aversive behaviour in mice. Neurosci Lett. 1988 Dec 19;95(1-3):281-5.
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Substance P(1-7) is a fragment of the neuropeptide, substance P (SP). Substance P(1-7) gives depressor and bradycardic effects when applied to the nucleus tractus solitarius.