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Sincalide

Name
Sincalide
Molecular structural formula
CAS Number
25126-32-3
Formula
C49H62N10O16S3
MW
1143.27
Sequence Shortening
D-{SO3H-Tyr}-MGWMDF-NH2
Sequence
Asp-{SO3H-Tyr}-Met-Gly-Trp-Met-Asp-Phe-NH2
InChIKey
IZTQOLKUZKXIRV-YRVFCXMDSA-N
Purity
≥98%
References
[1]. Wang C, Yu H, et al. Protective effect of cholecystokinin octapeptide on angiotensin II-induced apoptosis in H9c2 cardiomyoblast cells. J Cell Biochem. 2020;121(7):3560-3569. [2]. Wang C, Zhang C, et al. Cholecystokinin octapeptide reduces myocardial fibrosis and improves cardiac remodeling in post myocardial infarction rats. Int J Biochem Cell Biol. 2020;125:105793.
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Sincalide, also known as cholecystokinin octapeptide (CCK-8), is a synthetic octapeptide molecule. As a fast-acting amino acid peptide hormone analog of cholecystokinin (CCK), it retains most of the biological activity of CCK and plays its important physiological role.