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Home / Peptide products / Catalog peptides / S (187 species) / Sarafotoxin /
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Sarafotoxin S6a

Name
Sarafotoxin S6a
Molecular structural formula
Purity
≥95%
CAS Number
126738-34-9
Formula
C105H156N28O34S5
MW
2514.9
Target
Endothelin Receptor
Sequence
Cys-Ser-Cys-Lys-Asp-Met-Thr-Asp-Lys-Glu-Cys-Leu-Asn-Phe-Cys-His-Gln-Asp-Val-Ile-Trp (Disulfide bridge: Cys1- Cys15, Cys3-Cys11)
Sequence Shortening
CSCKDMTDKECLNFCHQDVIW (Disulfide bridge:Cys1-Cys15;Cys3-Cys11)
InChIKey
BOQKWORWRAYXSI-UHFFFAOYSA-N
References
[1]. P Schoeffter, et al. Differences between endothelin receptors mediating contraction of guinea-pig aorta and pig coronary artery. Eur J Pharmacol.
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Product details
Data download

Sarafotoxin S6a, a sarafotoxin analogue, is a endothelin receptor agonist and has an ETA/ETB selectivity profile similar to that of Endothelin-3. Sarafotoxin S6a elicits the pig coronary artery with an EC50 value of 7.5 nM.