CRO
CDMO
CMO
Testing services
Scientific Customized Peptides
General linear peptide synthesis
Long peptide synthesis
Cyclic peptide synthesis (staple peptide)
Cyclic peptide synthesis (disulfide ring formation)
Stable isotope labeling peptide synthesis
Glycopeptides
Polypeptide Modification
Peptide library synthesis
View all
Linker Synthesis Service
ADC Linker Synthesis Service
PDC Drug Synthesis Services
View all
FTE Services
PEPTIDE FTE
View all
Learn more
Popular peptides
Beauty peptides
Pharmaceutical peptide intermediates
Cancer antigenic peptide
Catalog peptides
Linker
Synthesis of unnatural amino acids and other blocks
Human body system
Tripeptide
Peptide Tag
Domain
Antagonist peptides
Blocker Peptides
Antimicrobial peptides
Amyloid peptides
Inhibitor peptides
View all
Bioanalytical drug development
RGD Peptides
Glycopeptides
Dipeptide
Cyclodipeptide
Substrate Peptide
View all
Nano Peptide
Self-assembling peptides
Cell-penetrating Peptides
View all
Learn more
Home / Peptide products / Linker / Reactive Linker / Amine Reactive Linker /
Filters
Popular peptides
Human body system
Tripeptide Peptide Tag Domain Antagonist peptides Blocker Peptides Antimicrobial peptides Amyloid peptides Inhibitor peptides Targeted Peptide Agonist Peptide
Bioanalytical drug development
RGD Peptides Glycopeptides Dipeptide Cyclodipeptide Substrate Peptide
Nano Peptide
Self-assembling peptides Cell-penetrating Peptides
Beauty peptides
Anti-aging
Anti-wrinkle, Firming Tissue cell regeneration Eye care
Anti-inflammatory
Anti-acne, Antibacterial Anti-allergic, Soothing
Repair
Epidermal repair Tissue repair
Moisturizing
Hydrate Lock water
Whitening
Blemishes Remove yellow and brighten
Body care
Promote hair growth Breast enlargement Burn fat
Pharmaceutical peptide intermediates
Neoplasm
Malignant tumors
Human Immunity
Immunomodulation Autoimmune
Diabetes
GLP-1 Glucagon
Hormones
Sex hormones Somatotropic hormone Angiotensin Vasopressin Oxytocin Others
Other
Digestive system Neurokinin Bone and joint Others
Cancer antigenic peptide
Mutation
Differentiation
Overexpressed
Tumor-specific
Catalog peptides
Linker
ADC Linker
Peptide Linker
PDC Linker
RDC linker
PROTAC linker
Reactive Linker
Alkyne Reactive Linker Amine Reactive Linker Azide Reactive Linker Click Reactive Linker Thiol Reactive Linker
Linker Intermediate
Advanced Linker Intermediate
Synthesis of unnatural amino acids and other blocks
Amino acids
Non-canonical amino acids
Fmoc protection

SPDB

Name
SPDB
Molecular structural formula
Purity
≥95%
CAS Number
115088-06-7
Formula
C13H14N2O4S2
MW
326.39
Target
ADC Linker
InChIKey
JSHOVKSMJRQOGY-UHFFFAOYSA-N
Solubility in DMSO
200 mg/mL
References
[1]. Widdison WC et al. Development of Anilino-Maytansinoid ADCs that Efficiently Release Cytotoxic Metabolitesin Cancer Cells andInduce High Levels of Bystander Killing. Bioconjug Chem, 2015 Nov 18, 26(11):2261-78.
* All products on our website are for scientific research and cannot be used in human body
Product details
Data download

SPDB is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs).