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Synthesis of unnatural amino acids and other blocks

SMCC

Name
SMCC
Molecular structural formula
Purity
≥95%
CAS Number
64987-85-5
MW
C16H18N2O6
MOLFile
334.32
Target
ADC Linker
InChIKey
JJAHTWIKCUJRDK-UHFFFAOYSA-N
Solubility in DMSO
25 mg/mL
Solubility in water
< 0.1 mg/mL
References
[1]. Guo Y, et al. Potent antigen-specific immune response induced by infusion of spleen cells coupled with succinimidyl-4-(N-maleimidomethyl cyclohexane)-1-carboxylate (SMCC) conjugated antigens. Int Immunopharmacol. 2016 Feb;31:158-68.
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SMCC is a protein crosslinker. SMCC-conjugated antigen coupled spleen cells to induce antigen-specific immune responses.