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RGDV

Name
RGDV
Molecular structural formula
Purity
95%
CAS Number
93674-99-8
Formula
C17H31N7O7
MW
445.47
Target
others
Sequence
Arg-Gly-Asp-Val
Sequence Shortening
RGDV
InChIKey
MDNRBNZIOBQHHK-KWBADKCTSA-N
References
[1]. Cadroy Y, et, al. RGDV peptide selectively inhibits platelet-dependent thrombus formation in vivo. Studies using a baboon model. J Clin Invest. 1989 Sep;84(3):939-44. [2]. Wang F, et, al. Preparation and biological evaluation of tumor-specific Ara-C liposomal preparations containing RGDV motif. J Pharm Sci. 2012 Dec;101(12):4559-68.
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Studies using a baboon model showed that RGDV selectively inhibits platelet-dependent thrombus formation in vivo. In a study by Kawahara et al. on the inhibitory effects of adhesion oligopeptides on the invasion of squamous carcinoma cells RGDV was the most effective inhibitor amongst the evaluated peptides.