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Prolactin Releasing Peptide (1-31), HumanPrRP-31

Name
Prolactin Releasing Peptide (1-31), HumanPrRP-31
Molecular structural formula
Purity
≥95%
CAS Number
215510-22-8
Formula
C160H252N56O42S
MW
3664.2
Target
GnRH Receptor
Sequence
Ser-Arg-Thr-His-Arg-His-Ser-Met-Glu-Ile-Arg-Thr-Pro-Asp-Ile-Asn-Pro-Ala-Trp-Tyr-Ala-Ser-Arg-Gly-Ile-Arg-Pro-Val-Gly-Arg-Phe-NH2
Sequence Shortening
SRTHRHSMEIRTPDINPAWYASRGIRPVGRF-NH2
InChIKey
CPYRNXJVNKJULS-FWGIIJIJSA-N
References
[1]. Langmead CJ, et al. Characterization of the binding of [(125)I]-human prolactin releasing peptide (PrRP) to GPR10, a novel G protein coupled receptor. Characterization of the binding of [(125)I]-human prolactin releasing peptide (PrRP) to GPR10, a novel G protein coupled receptor. [2]. L J Seal, et al. Prolactin releasing peptide (PrRP) stimulates luteinizing hormone (LH) and follicle stimulating hormone (FSH) via a hypothalamic mechanism in male rats. Endocrinology. 2000 May;141(5):1909-12.
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Product details
Data download

Prolactin Releasing Peptide (1-31), human is a high affinity GPR10 ligand that cause the release of the prolactin. Prolactin Releasing Peptide (1-31) binds to GPR10 for human and rats with Ki values of 1.03 nM and 0.33 nM, respectively. Prolactin Releasing Peptide (1-31) can be used for the research of the hypothalamo-pituitary axis.