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Synthesis of unnatural amino acids and other blocks

Procathepsin B (26-50) (rat)

Name
Procathepsin B (26-50) (rat)
Molecular structural formula
Purity
≥95%
CAS Number
317331-27-4
Formula
C123H198N34O33S
MW
2713.16
Sequence
Ala-Gly-Arg-Asn-Phe-Tyr-Asn-Val-Asp-Ile-Ser-Tyr-Leu-Lys-Lys-Leu-Cys-Gly-Thr-Val-Leu-Gly-Gly-Pro-Lys-NH2|H-Ala-Gly-Arg-Asn-Phe-Tyr-Asn-Val-Asp-Ile-Ser-Tyr-Leu-Lys-Lys-Leu-Cys-Gly-Thr-Val-Leu-Gly-Gly-Pro-Lys-NH2
Sequence Shortening
AGRNFYNVDISYLKKLCGTVLGGPK-NH2
InChIKey
ZFCIHFPJJWSJMS-HGVIYXBOSA-N
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Product details
Data download

This 25 residue peptide was completely resistant to proteolysis by cathepsin B even after incubation overnight. It inhibited human cathepsin B with Ki = 2.8 µM and rat cathepsin B with Ki = 2 µM.