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Synthesis of unnatural amino acids and other blocks

Prepro-ANF (56-92), human

Name
Prepro-ANF (56-92), human
Molecular structural formula
Purity
≥95%
CAS Number
112199-06-1
Formula
C31H32N4O2
MW
492.61
Target
Guanylate Cyclase
Sequence
Glu-Val-Val-Pro-Pro-Gln-Val-Leu-Ser-Glu-Pro-Asn-Glu-Glu-Ala-Gly-Ala-Ala-Leu-Ser-Pro-Leu-Pro-Glu-Val-Pro-Pro-Trp-Thr-Gly-Glu-Val-Ser-Pro-Ala-Gln-Arg
Sequence Shortening
EVVPPQVLSEPNEEAGAALSPLPEVPPWTGEVSPAQR
References
[1]. Vesely DL, et al. Human prepro atrial natriuretic factors 26-55, 56-92, and 104-123 increase renal guanylate cyclase activity. Biochem Biophys Res Commun. 1987 Feb 27;143(1):186-93.
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Prepro-ANF (56-92), human is a human atrial natriuretic factor precursor. Prepro-ANF (56-92), human is also a guanylate cyclase activator that enhances particulate guanylate cyclase activity in the renal membrane and renal unit.