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Advanced Linker Intermediate
Synthesis of unnatural amino acids and other blocks
Amino acids
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Fmoc protection

Phe-Lys(Fmoc)-PAB

Name
Phe-Lys(Fmoc)-PAB
Molecular structural formula
CAS Number
2149584-03-0
Formula
C37H40N4O5
MW
620.74
InChIKey
RCPHMUPZDFKBDS-HEVIKAOCSA-N
DMSO solubility
100 mg/mL
Purity
≥95%
References
[1]. Abu Ajaj K, et al. Development of protein-binding bifunctional linkers for a new generation of dual-actingprodrugs. Bioconjug Chem. 2009 Feb;20(2):390-6.
Target
ADC Linker
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Product details
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Phe-Lys(Fmoc)-PAB is a cathepsin cleavable ADC linker used for the antibody-drug conjugates (ADCs).