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Synthesis of unnatural amino acids and other blocks

PEG3-CH2COOtBu

Name
PEG3-CH2COOtBu
Molecular structural formula
Purity
≥95%
CAS Number
189808-70-6
Formula
C12H25NO5
MW
263.33
Target
PROTAC Linkers
InChIKey
OTTHWLFOQWLZKB-UHFFFAOYSA-N
Solubility in DMSO
100 mg/mL
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.
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NH2-PEG3-C1-Boc (PROTAC Linker 5) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.